Measuring visceral pain in patients with Irritable Bowel Syndrome
Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain
This study is looking for a new way to measure the belly pain that people with Irritable Bowel Syndrome (IBS) feel, so that doctors can better understand it and create more effective treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Storrs NIH-funded |
| Lab location | 1 site (Storrs-Mansfield, United States) |
| Project ID | NIH-11145911 on NIH RePORTER |
What this research studies
This research aims to develop an objective method to quantify visceral pain experienced by patients with Irritable Bowel Syndrome (IBS). By utilizing an integrated multimodal electrophysiological index, the study will assess autonomic nervous system activity and abdominal muscle contractions in relation to pain levels. This approach seeks to provide a reliable biomarker for visceral pain, moving beyond subjective patient reports that can be influenced by placebo effects. The ultimate goal is to facilitate the development of more effective treatments for IBS pain.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Irritable Bowel Syndrome who experience significant visceral pain.
Not a fit: Patients without a diagnosis of Irritable Bowel Syndrome or those who do not experience visceral pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients suffering from IBS-related visceral pain.
How similar studies have performed: While the approach of using electrophysiological indices is innovative, similar studies have shown promise in correlating autonomic nervous system activity with pain perception.
Where this research is happening
Storrs-Mansfield, United States
- University of Connecticut Storrs — Storrs-Mansfield, United States (Active)
Researchers
- Principal investigator: Posada-Quintero, Hugo Fernando — University of Connecticut Storrs
- Study coordinator: Posada-Quintero, Hugo Fernando
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.