Measuring the viability of liver transplants using advanced spectroscopy techniques
A quantitative viability metric for liver transplantation using Resonance Raman Spectroscopy
['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11051898
This study is looking at a new way to quickly check if a liver is healthy enough for transplant, especially for those that might be a little damaged, so that more people in need of a liver can get one.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11051898 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the viability assessment of liver transplants by utilizing Resonance Raman Spectroscopy. The goal is to develop a quantitative metric that can quickly and accurately determine whether a liver organ is suitable for transplantation, especially for those that are marginally damaged. By enhancing the evaluation process, the research aims to reduce the number of viable organs that are discarded and increase the availability of transplants for patients in need. The methodology involves real-time analysis of organ viability, which could significantly streamline the transplantation process.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients on the waiting list for liver transplants, particularly those with end-stage liver disease.
Not a fit: Patients who are not candidates for liver transplantation or those with conditions that preclude them from receiving a transplant may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more available liver transplants, potentially saving lives and improving outcomes for patients with end-stage liver disease.
How similar studies have performed: Other research has shown promise in using advanced spectroscopy techniques for organ viability assessment, indicating that this approach could be a significant advancement in the field.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TESSIER, SHANNON NOELLA — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: TESSIER, SHANNON NOELLA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.