Measuring the function of eye drainage structures to improve glaucoma treatment

OCT Measurement of Trabecular Meshwork Function In Vivo

NIH-funded research Georgia Institute of Technology · NIH-10706947

This study is testing a new way to use special imaging technology to measure how stiff a part of your eye called the trabecular meshwork is, which helps control eye pressure and is important for diagnosing and treating glaucoma.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionGeorgia Institute of Technology NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-10706947 on NIH RePORTER

What this research studies

This research aims to develop a new method using optical coherence tomography (OCT) to measure the stiffness of the trabecular meshwork, a key structure involved in regulating intraocular pressure (IOP) in the eye. By imaging the trabecular meshwork and Schlemm’s canal while manipulating IOP, researchers will quantify changes in the canal size and assess the stiffness of the meshwork. This innovative approach seeks to provide a more patient-friendly and accurate assessment of trabecular meshwork function, which is crucial for diagnosing and treating glaucoma effectively.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with glaucoma or those at risk of developing elevated intraocular pressure.

Not a fit: Patients with normal intraocular pressure and no history of glaucoma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic techniques for glaucoma, potentially preventing blindness in patients by allowing for better management of intraocular pressure.

How similar studies have performed: While the approach of using OCT for this purpose is innovative, previous studies have shown success in related imaging techniques for assessing eye structures, indicating potential for this novel method.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.