Measuring the elastic properties of hydrogels using acoustic force microscopy
Official title: Development of two-dimensional (2D) acoustic force elastography microscopy for the non-contact measurement of elastic property of cell encapsulated scaffolds
Funded at University of Southern California · NIH-11080287 · Data updated 2026-11-12
This study is testing a new, gentle way to measure how stretchy and firm special gel-like materials called hydrogels are, which are important for helping heal wounds and repair tissues in the body.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | May 1, 2024 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $164,098 |
| NIH project number | 5R21GM154167-02 |
| Project ID | NIH-11080287 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals requiring advanced wound healing solutions or those undergoing tissue engineering procedures.
✕Less likely to help
Patients who do not require tissue engineering or have no need for improved wound healing solutions may not benefit from this research.
What this research studies
This research focuses on developing a new technique called two-dimensional acoustic force elastography microscopy to measure the elastic properties of hydrogels, which are crucial for tissue engineering. Hydrogels mimic the natural environment of cells and are used in various biomedical applications, including wound healing and tissue repair. By using non-contact methods, this research aims to provide a more accurate and less destructive way to assess the mechanical properties of these materials over time, which is essential for their effective use in medical treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved biomaterials that better integrate with human tissues, enhancing healing and recovery processes.
How similar studies have gone: Previous research has shown promise in using acoustic methods for material characterization, indicating potential success for this novel approach.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Liu, Hsiao-Chuan — University of Southern California
- Study coordinator: Liu, Hsiao-Chuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.