Measuring swallowing pressures to improve treatment outcomes for difficulty swallowing
Defining novel pharyngeal pressure metrics to predict dysphagia treatment outcomes and clinical prognosis using high-resolution manometry
['FUNDING_OTHER'] · WM S. MIDDLETON MEMORIAL VETERANS HOSP · NIH-11194228
This study is looking at a new way to measure how well people with swallowing difficulties can swallow, using a special test, to help doctors understand how treatments are working and improve care for those with oropharyngeal dysphagia.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WM S. MIDDLETON MEMORIAL VETERANS HOSP (nih funded) |
| Locations | 1 site (MADISON, UNITED STATES) |
| Trial ID | NIH-11194228 on ClinicalTrials.gov |
What this research studies
This research investigates the use of pharyngeal high-resolution manometry (pHRM) to objectively measure swallowing pressures in patients with oropharyngeal dysphagia, a condition that makes swallowing difficult. By integrating pHRM into standard assessments, the research aims to provide clearer insights into how treatments affect swallowing function and to develop algorithms that predict treatment outcomes. This approach seeks to bridge the gap between objective physiological measurements and patient-reported outcomes, ultimately enhancing dysphagia management.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults experiencing oropharyngeal dysphagia, particularly those who have undergone or are undergoing treatment for this condition.
Not a fit: Patients without swallowing difficulties or those who do not meet the age criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with swallowing difficulties, improving their quality of life.
How similar studies have performed: Previous research has shown promise in using objective measures like pHRM to assess swallowing function, indicating that this approach could be beneficial.
Where this research is happening
MADISON, UNITED STATES
- WM S. MIDDLETON MEMORIAL VETERANS HOSP — MADISON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCCULLOCH, TIMOTHY M — WM S. MIDDLETON MEMORIAL VETERANS HOSP
- Study coordinator: MCCULLOCH, TIMOTHY M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.