Measuring swallowing pressures to improve treatment outcomes for difficulty swallowing
Official title: Defining novel pharyngeal pressure metrics to predict dysphagia treatment outcomes and clinical prognosis using high-resolution manometry
Funded at Wm S. Middleton Memorial Veterans Hosp · NIH-11194228 · Data updated 2026-11-12
This study is looking at a new way to measure how well people with swallowing difficulties can swallow, using a special test, to help doctors understand how treatments are working and improve care for those with oropharyngeal dysphagia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wm S. Middleton Memorial Veterans Hosp NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | October 1, 2020 |
| Project end | September 30, 2025 |
| Funding year | 2025 |
| NIH project number | 5I01RX003221-05 |
| Project ID | NIH-11194228 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults experiencing oropharyngeal dysphagia, particularly those who have undergone or are undergoing treatment for this condition.
✕Less likely to help
Patients without swallowing difficulties or those who do not meet the age criteria may not benefit from this research.
What this research studies
This research investigates the use of pharyngeal high-resolution manometry (pHRM) to objectively measure swallowing pressures in patients with oropharyngeal dysphagia, a condition that makes swallowing difficult. By integrating pHRM into standard assessments, the research aims to provide clearer insights into how treatments affect swallowing function and to develop algorithms that predict treatment outcomes. This approach seeks to bridge the gap between objective physiological measurements and patient-reported outcomes, ultimately enhancing dysphagia management.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with swallowing difficulties, improving their quality of life.
How similar studies have gone: Previous research has shown promise in using objective measures like pHRM to assess swallowing function, indicating that this approach could be beneficial.
Where this research is happening
-
Wm S. Middleton Memorial Veterans Hosp
Madison, United States Active
Researchers
- Principal investigator: Mcculloch, Timothy M — Wm S. Middleton Memorial Veterans Hosp
- Study coordinator: Mcculloch, Timothy M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.