Measuring myelin loss and recovery in stroke patients
Quantitative clinical imaging of demyelination and remyelination in ischemic stroke
This study is looking at how a part of the brain called myelin is affected after a stroke, using special MRI scans to see how it changes over time, and it’s for people who have had an ischemic stroke to help understand their recovery better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11046910 on NIH RePORTER |
What this research studies
This research investigates how myelin, a crucial component of brain structure, is affected in patients who have experienced an ischemic stroke. By using advanced magnetic resonance imaging (MRI) techniques, the study aims to quantify the loss and recovery of myelin in stroke patients, linking these changes to clinical outcomes and functional recovery. The research will also explore the relationship between myelin damage and the overall extent of brain injury, providing insights into the healing process after a stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently suffered an ischemic stroke and are undergoing rehabilitation.
Not a fit: Patients who have not experienced a stroke or have chronic neurological conditions unrelated to ischemic stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment strategies for stroke patients, enhancing recovery outcomes.
How similar studies have performed: Previous animal studies have shown promising results regarding myelin damage and repair in stroke, but this research aims to translate those findings into clinical practice, making it a novel approach.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Yarnykh, Vasily L. — University of Washington
- Study coordinator: Yarnykh, Vasily L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.