Measuring muscle energy levels in patients with peripheral artery disease using advanced MRI techniques
Monitoring Oxidative Capacity in Peripheral Artery Disease Patients using MR Imaging
This study is looking at a new MRI method to help doctors see how well your muscles are working and recovering if you have peripheral artery disease (PAD), which could lead to better treatments and care for you.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10468146 on NIH RePORTER |
What this research studies
This research investigates how to monitor oxidative capacity in patients with peripheral artery disease (PAD) using a novel MRI technique. The study aims to identify early signs of PAD and assess the effectiveness of treatments like supervised exercise and surgical interventions. By utilizing a new imaging method called creatine chemical exchange saturation transfer (CrCEST), the researchers hope to provide a more accurate and noninvasive way to evaluate muscle energy levels and recovery in these patients. This could lead to better management and outcomes for individuals suffering from PAD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with peripheral artery disease, particularly those experiencing atypical symptoms or at risk of serious complications.
Not a fit: Patients without peripheral artery disease or those with advanced stages of the disease that do not respond to standard treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment strategies for patients with peripheral artery disease, enhancing their quality of life.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for monitoring muscle energy levels, suggesting that this approach could yield valuable insights for PAD management.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Kumar, Dushyant — University of Pennsylvania
- Study coordinator: Kumar, Dushyant
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.