Measuring mitral valve leakage using advanced MRI and deep learning techniques
Official title: Mitral Regurgitation Quantification Using Dual-venc 4D flow MRI and Deep learning
Funded at Northwestern University at Chicago · NIH-10907639 · Data updated 2026-11-12
This study is testing a new way to check how well your heart is working if you have mitral valvular regurgitation, using advanced MRI technology and smart computer tools to give a clearer picture of blood flow, so you can get better care and treatment for your heart.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $240,000 |
| NIH project number | 5R21HL168612-02 |
| Project ID | NIH-10907639 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with mitral valvular regurgitation who require precise assessment of their condition.
✕Less likely to help
Patients without mitral valve regurgitation or those who do not require advanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on improving the assessment of mitral valvular regurgitation (MVR), a common heart condition affecting many individuals. It utilizes advanced 4D flow MRI technology combined with deep learning algorithms to provide a more accurate and direct quantification of blood flow dynamics in the heart. By overcoming the limitations of traditional echocardiography, this approach aims to enhance the precision of MVR diagnosis and monitoring, which is crucial for timely treatment decisions. Patients will benefit from a more reliable evaluation of their condition, potentially leading to better management of their heart health.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and improved treatment strategies for patients with mitral valve regurgitation.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for cardiac assessments, suggesting that this approach could yield significant advancements in the field.
Where this research is happening
-
Northwestern University at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Lee, Jeesoo — Northwestern University at Chicago
- Study coordinator: Lee, Jeesoo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.