Measuring inflammation in the eye using advanced imaging techniques
Official title: Objective quantification of vitreous inflammation using optical coherence tomography
Funded at University of California Los Angeles · NIH-10770507 · Data updated 2026-11-12
This study is looking for ways to better measure eye inflammation in people with uveitis, using a special imaging technique called OCT, to help improve treatment and protect your vision over the next year.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $196,916 |
| NIH project number | 5R21EY034543-02 |
| Project ID | NIH-10770507 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 16 and older who have active non-infectious intermediate, posterior, or panuveitis in at least one eye.
✕Less likely to help
Patients with infectious uveitis or those who do not meet the age or condition criteria may not benefit from this research.
What this research studies
This research focuses on improving the assessment of vitreous inflammation in patients with uveitis, a condition that can lead to vision impairment. By utilizing optical coherence tomography (OCT), the study aims to develop a more objective and quantitative method for evaluating inflammation compared to traditional grading systems. Participants will be involved in a clinical trial where their eye inflammation will be monitored over a 12-month period using standardized OCT imaging. This approach seeks to enhance the accuracy of inflammation measurements and potentially improve treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of eye inflammation, allowing for better treatment decisions and improved vision outcomes for patients.
How similar studies have gone: Previous research has shown success in using optical coherence tomography for assessing ocular conditions, indicating that this approach has potential for effective application in this study.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Tsui, Edmund — University of California Los Angeles
- Study coordinator: Tsui, Edmund
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.