Measuring inflammation in the eye using advanced imaging techniques
Objective quantification of vitreous inflammation using optical coherence tomography
['FUNDING_R21'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10770507
This study is looking for ways to better measure eye inflammation in people with uveitis, using a special imaging technique called OCT, to help improve treatment and protect your vision over the next year.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10770507 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the assessment of vitreous inflammation in patients with uveitis, a condition that can lead to vision impairment. By utilizing optical coherence tomography (OCT), the study aims to develop a more objective and quantitative method for evaluating inflammation compared to traditional grading systems. Participants will be involved in a clinical trial where their eye inflammation will be monitored over a 12-month period using standardized OCT imaging. This approach seeks to enhance the accuracy of inflammation measurements and potentially improve treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 16 and older who have active non-infectious intermediate, posterior, or panuveitis in at least one eye.
Not a fit: Patients with infectious uveitis or those who do not meet the age or condition criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of eye inflammation, allowing for better treatment decisions and improved vision outcomes for patients.
How similar studies have performed: Previous research has shown success in using optical coherence tomography for assessing ocular conditions, indicating that this approach has potential for effective application in this study.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TSUI, EDMUND — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: TSUI, EDMUND
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease Frequency Surveys, Disorder, Disease