Measuring important molecules in blood and cells for better health insights
Quantitative Analysis of Labile Metabolites in Biological Samples
This study is working on better ways to measure important substances in your blood and cells that help keep your body healthy, especially since problems with these substances can be linked to diseases like cancer and heart failure.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10844620 on NIH RePORTER |
What this research studies
This research focuses on developing reliable methods to measure coenzymes and antioxidants in biological samples, particularly blood and cells. These molecules play a crucial role in cellular functions and their dysfunction is linked to various diseases, including cancer and heart failure. The study aims to overcome challenges in accurately measuring these unstable metabolites using advanced techniques like nuclear magnetic resonance (NMR) spectroscopy. By improving measurement methods, the research hopes to provide better insights into the role of these molecules in health and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to cellular dysfunction, such as cancer, heart failure, diabetes, and those experiencing aging-related health issues.
Not a fit: Patients with stable health and no underlying conditions related to cellular dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for diseases related to cellular dysfunction.
How similar studies have performed: Other research has shown promise in measuring metabolites using advanced techniques, but this specific approach is innovative and aims to fill a significant gap in current methodologies.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Gowda, G. a. Nagana — University of Washington
- Study coordinator: Gowda, G. a. Nagana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.