Measuring how well patients with HIV stick to their medication
New Pharmacologic Measures of ART Adherence and Exposure: Pathway to Clinical Implementation
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10611354
This study is exploring a new way to check if people with HIV are taking their medication as prescribed by looking at a specific marker in their blood, which could help improve treatment success.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10611354 on ClinicalTrials.gov |
What this research studies
This research investigates a new way to measure adherence to antiretroviral therapy (ART) in people living with HIV. It focuses on analyzing a specific biomarker, tenofovir diphosphate (TFV-DP), found in dried blood spots to determine how well patients are following their medication regimen. By understanding the pharmacology of this biomarker, the research aims to improve the accuracy of adherence assessments and ultimately enhance treatment outcomes. The study will specifically look at TFV-DP levels from a newer type of ART, TAF, to fill existing knowledge gaps.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are currently on antiretroviral therapy.
Not a fit: Patients who are not on ART or those with conditions unrelated to HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of medication adherence, improving treatment strategies for patients with HIV.
How similar studies have performed: Previous research has shown promise in using biomarkers for adherence measurement, but this specific approach with TAF is novel and untested.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ANDERSON, PETER L. — UNIVERSITY OF COLORADO DENVER
- Study coordinator: ANDERSON, PETER L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.