Measuring how the heart uses oxygen in patients with heart damage without using contrast agents

MR Quantification of Myocardial Oxygen Utilization in Chronic Myocardial Infarction without Contrast

NIH-funded research Illinois Institute of Technology · NIH-10581563

This study is testing a new, safer MRI method to see how well the heart uses oxygen in people who have had a heart attack, helping doctors make better treatment choices without the need for invasive procedures.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIllinois Institute of Technology NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10581563 on NIH RePORTER

What this research studies

This research aims to develop a new Magnetic Resonance Imaging (MRI) technique that quantifies how the heart utilizes oxygen in patients who have experienced a myocardial infarction, or heart attack. By using a non-invasive approach, this method seeks to provide a safer and more effective imaging test compared to traditional methods that often require contrast agents and expose patients to radiation. The study focuses on improving the assessment of heart function and viability, which could lead to better treatment decisions for patients with coronary artery disease. The research is particularly relevant for those who may not benefit from current invasive procedures.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have suffered from a myocardial infarction and are being evaluated for coronary artery disease.

Not a fit: Patients who do not have a history of heart attacks or significant coronary artery disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer and more accurate assessments of heart health, ultimately improving treatment outcomes for patients with heart disease.

How similar studies have performed: While the approach of using MRI for cardiac assessment is established, the specific method of quantifying oxygen utilization without contrast is novel and has not been extensively tested.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.