Measuring how enteric pathogens spread and how to reduce infections in children
Serologic measures of enteric pathogen transmission for intervention studies and population monitoring in low-resource settings
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10874624
This study is looking at how germs that cause stomach infections spread among kids in places with limited resources, and it aims to find out if better nutrition and environmental changes can help keep them healthier.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10874624 on ClinicalTrials.gov |
What this research studies
This research investigates the transmission of enteric pathogens among children in low-resource settings, focusing on how environmental interventions and improved nutrition can reduce infections. The team uses advanced multiplex bead assays to measure the immune response to various pathogens, providing insights into how these infections spread. By combining antibody response data with spatial epidemiology, the research aims to identify communities most affected by multiple pathogens and evaluate the effectiveness of interventions. This approach allows for a better understanding of infection dynamics and the impact of public health programs.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under the age of 11 living in low-resource settings, particularly those at risk for enteric infections.
Not a fit: Patients who are not children or those living in high-resource settings may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective public health strategies that significantly reduce enteric infections in children.
How similar studies have performed: Previous cluster randomized trials in Kenya and Bangladesh have shown success in implementing interventions to reduce enteric infections, suggesting that this approach has potential for further advancements.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ARNOLD, BENJAMIN F — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: ARNOLD, BENJAMIN F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.