NIH-funded research R21 grant

Measuring gastrointestinal symptoms in autistic individuals

Official title: Development and Psychometric Evaluation of Gastrointestinal Symptom Measures in Autistic Children and Adults

Funded at Hugo W. Moser Res Inst Kennedy Krieger · NIH-10808460 · Data updated 2026-11-12

This study is working on a new tool to help parents report their child's tummy troubles and related behaviors, making it easier for doctors to recognize and treat gastrointestinal issues in kids and adults with autism.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionHugo W. Moser Res Inst Kennedy Krieger
NIH-funded
Lab location1 site (Baltimore, United States)
Project startAugust 12, 2024
Project endJuly 31, 2026
Funding year2024
Award (this year)$340,604
NIH project number1R21HD111609-01A1
Project IDNIH-10808460 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include autistic children and adults experiencing gastrointestinal symptoms such as abdominal pain or acid reflux.

Less likely to help

Patients without gastrointestinal symptoms or those not on the autism spectrum may not benefit from this research.

What this research studies

This research focuses on developing and evaluating new measures to accurately assess gastrointestinal (GI) symptoms in children and adults on the autism spectrum. It aims to address the barriers that autistic individuals face in having their GI symptoms recognized and treated. The study involves creating a comprehensive parent-report measure called the Autism Gastrointestinal and Related Behaviors Inventory (GIRBI), which captures a wide range of GI signs and symptoms, including those related to mealtime behaviors and non-verbal indicators of distress. By improving the measurement of GI symptoms, the research seeks to enhance the screening and diagnosis of GI conditions in this population.

Why it matters

Potential benefit: If successful, this research could lead to better recognition and treatment of gastrointestinal issues in autistic individuals, improving their overall quality of life.

How similar studies have gone: Previous research has highlighted the need for improved GI symptom measures in autistic populations, indicating that this approach is both necessary and timely.

Where this research is happening

  • Hugo W. Moser Res Inst Kennedy Krieger
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Holingue, Calliope — Hugo W. Moser Res Inst Kennedy Krieger
  • Study coordinator: Holingue, Calliope

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.