Measuring exosome release from brain tissue cultures
Official title: New technologies for in situ measurement of exosome release from brain slice cultures
Funded at New Mexico State University Las Cruces · NIH-10910102 · Data updated 2026-11-12
This study is looking at tiny bubbles called exosomes that help brain cells talk to each other, and it aims to find out how this communication affects brain health, especially in relation to sleep patterns, which could help people with neurological and metabolic disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New Mexico State University Las Cruces NIH-funded |
| Lab location | 1 site (Las Cruces, United States) |
| Project start | September 16, 2020 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $342,059 |
| NIH project number | 5R35GM138173-05 |
| Project ID | NIH-10910102 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurological or metabolic disorders that may involve disrupted intercellular communication.
✕Less likely to help
Patients with conditions unrelated to neurological or metabolic disorders may not receive any benefit from this research.
What this research studies
This research focuses on understanding how small lipid vesicles, known as exosomes, facilitate communication between brain cells. By developing advanced tools for analyzing these exosomes in brain slice cultures, the researchers aim to uncover new mechanisms that may contribute to various diseases. The study involves creating specialized systems for sampling and quantifying exosome release, particularly in relation to circadian rhythms in the brain. Patients may benefit from insights gained into how disrupted cell communication can lead to neurological and metabolic disorders.
Why it matters
Potential benefit: If successful, this research could lead to new therapies targeting communication breakdowns in neurological and metabolic disorders.
How similar studies have gone: Other research has shown promise in understanding exosome roles in cell communication, suggesting that this approach could yield valuable insights.
Where this research is happening
-
New Mexico State University Las Cruces
Las Cruces, United States Active
Researchers
- Principal investigator: Baker, Christopher a — New Mexico State University Las Cruces
- Study coordinator: Baker, Christopher a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.