Measuring brain oxygen use in newborns with MRI
Assessment of brain oxygen consumption in neonates using MRI
['FUNDING_R01'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-10676217
This study is looking at how a lack of oxygen during birth can impact newborns' brains and aims to create a safe MRI method to check how well their brains are using oxygen, helping doctors better understand any potential brain injuries and improve care for these babies.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MARYLAND BALTIMORE (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-10676217 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how oxygen deprivation during birth affects the brains of newborns. It aims to develop a non-invasive MRI technique to measure brain oxygen consumption and extraction rates, which are critical for assessing brain injury caused by birth asphyxia. By identifying reliable biomarkers, the research seeks to improve the prediction of clinical outcomes for affected infants. This innovative approach could provide valuable insights into the extent of brain injury without the need for invasive procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns who have experienced birth asphyxia or are at risk of hypoxic brain injuries.
Not a fit: Patients who are not newborns or who have not experienced any form of birth asphyxia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better assessment and management of brain injuries in newborns, ultimately improving their long-term health outcomes.
How similar studies have performed: While there have been successful studies using MRI for brain imaging, the specific approach of measuring oxygen consumption in neonates is novel and has not been extensively tested.
Where this research is happening
BALTIMORE, UNITED STATES
- UNIVERSITY OF MARYLAND BALTIMORE — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, PEIYING — UNIVERSITY OF MARYLAND BALTIMORE
- Study coordinator: LIU, PEIYING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.