Measuring brain changes in Alzheimer's patients during treatment
Quantification of ARIA During the Treatment of Alzheimer's Patients
['FUNDING_SBIR_2'] · CORTECHS LABS, INC. · NIH-10917839
This study is looking at how a new Alzheimer's treatment called aducanumab affects the brain, using special MRI scans to help doctors spot any changes more easily, so they can better monitor patients and improve their care.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORTECHS LABS, INC. (nih funded) |
| Locations | 1 site (San Diego, UNITED STATES) |
| Trial ID | NIH-10917839 on ClinicalTrials.gov |
What this research studies
This research focuses on detecting and quantifying changes in the brains of Alzheimer's patients who are receiving treatment with amyloid-clearing drugs, specifically aducanumab. Using advanced MRI imaging techniques, the study aims to develop software that can automatically identify and measure abnormalities related to the treatment, known as amyloid-related imaging abnormalities (ARIA). By improving the detection of these changes, the research seeks to enhance patient monitoring and treatment outcomes. The goal is to create a clinically usable tool that can assist healthcare providers in making informed decisions about patient care.
Who could benefit from this research
Good fit: Ideal candidates for this research are Alzheimer's patients who are starting treatment with aducanumab or similar amyloid-targeting therapies.
Not a fit: Patients who are not undergoing treatment with amyloid-clearing drugs or those with other forms of dementia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring of Alzheimer's patients during treatment, potentially improving their outcomes and quality of life.
How similar studies have performed: Previous research has shown promise in using imaging techniques to monitor treatment effects in Alzheimer's patients, indicating that this approach could be effective.
Where this research is happening
San Diego, UNITED STATES
- CORTECHS LABS, INC. — San Diego, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ULUG, AZIZ M — CORTECHS LABS, INC.
- Study coordinator: ULUG, AZIZ M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease patient