Measuring brain and blood markers of dementia in middle-aged autistic adults
Quantification of the neurocognitive, brain, and blood markers of dementia in middle-aged autistic adults
This study is looking at how early signs of dementia show up in autistic adults between 40 and 65 years old by checking their memory, thinking skills, and brain scans, with the goal of finding better ways to diagnose and treat dementia for people with autism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11093338 on NIH RePORTER |
What this research studies
This research investigates the early signs of dementia in autistic adults aged 40-65 by analyzing neurocognitive performance, brain imaging, and blood biomarkers. The study aims to identify specific changes in memory and executive function, as well as the presence of amyloid proteins in the brain and blood that may indicate the onset of dementia. By utilizing advanced imaging techniques and biomarker analysis, the research seeks to provide a clearer understanding of how dementia manifests in individuals with autism spectrum disorder. This could lead to more tailored diagnostic and treatment approaches for this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are middle-aged adults aged 40-65 who have a diagnosis of autism spectrum disorder.
Not a fit: Patients outside the age range of 40-65 or those without a diagnosis of autism spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier detection and better management of dementia in autistic adults, improving their quality of life.
How similar studies have performed: While there is emerging evidence regarding dementia in autistic adults, this research approach is relatively novel and aims to fill significant gaps in understanding.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Wang, Zheng — University of Florida
- Study coordinator: Wang, Zheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.