Measuring brain activity during cognitive tasks using non-invasive techniques
The TMS-evoked potential as a measure of cortical excitation and inhibition during cognitive processes
['FUNDING_R21'] · UNIVERSITY OF IOWA · NIH-10931205
This study is looking at how a gentle brain stimulation technique can help us understand how different parts of the brain work when we’re using our memory and attention, especially focusing on an area that helps with eye movements and thinking.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF IOWA (nih funded) |
| Locations | 1 site (IOWA CITY, UNITED STATES) |
| Trial ID | NIH-10931205 on ClinicalTrials.gov |
What this research studies
This research investigates how non-invasive brain stimulation can measure the excitability of different brain regions during cognitive processes. By applying transcranial magnetic stimulation (TMS) and recording the resulting brain activity through EEG, the study aims to understand how the brain's cortical regions respond to tasks that require memory and attention. The researchers will focus on the frontal eye fields, a brain area involved in eye movements and cognitive functions, to see how its excitability changes during specific cognitive tasks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cognitive impairments or those interested in understanding brain function related to memory and attention.
Not a fit: Patients with severe neurological disorders or those unable to participate in cognitive tasks may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment of cognitive disorders by providing insights into brain function and excitability.
How similar studies have performed: Previous research has shown success in using TMS and EEG to study brain activity, indicating that this approach is promising and has potential for significant findings.
Where this research is happening
IOWA CITY, UNITED STATES
- UNIVERSITY OF IOWA — IOWA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WESSEL, JAN R — UNIVERSITY OF IOWA
- Study coordinator: WESSEL, JAN R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.