Measuring blood flow in the lungs using advanced imaging techniques
Quantitative magnetic resonance imaging of pulmonaryperfusion
This study is looking at how blood flows in the lungs of people with idiopathic pulmonary fibrosis (IPF) using a special type of MRI, which could help us understand the disease better and lead to new treatments to improve care for patients.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10947547 on NIH RePORTER |
What this research studies
This research aims to develop a model that accurately measures blood flow and microvascular changes in the lungs, particularly in patients with idiopathic pulmonary fibrosis (IPF). By using dynamic contrast-enhanced MRI, the study will analyze how a contrast agent moves through lung tissues, providing insights into blood flow and vascular permeability. The findings could help clarify the mechanisms behind lung fibrosis and improve understanding of the disease's progression. Ultimately, this research seeks to enhance patient care and support the development of new treatments for IPF.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with idiopathic pulmonary fibrosis or related pulmonary conditions.
Not a fit: Patients with other forms of lung disease that do not involve pulmonary fibrosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment strategies for patients suffering from idiopathic pulmonary fibrosis.
How similar studies have performed: Previous studies using dynamic contrast-enhanced MRI have shown promise in assessing lung conditions, indicating that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Zhou, Iris Yuwen — Massachusetts General Hospital
- Study coordinator: Zhou, Iris Yuwen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.