Measuring blood flow in the brain using advanced optical techniques
Official title: Coherence engineering of a human brain interferometer to quantitatively and specifically measure cerebral blood flow
Funded at New York University School of Medicine · NIH-11058777 · Data updated 2026-11-12
This study is testing a new way to measure blood flow in the brain for patients who have had a subarachnoid hemorrhage, aiming to help doctors catch any problems earlier and improve recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 11, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $580,654 |
| NIH project number | 1R01EB035762-01A1 |
| Project ID | NIH-11058777 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have suffered from subarachnoid hemorrhage and are at risk for delayed cerebral ischemia.
✕Less likely to help
Patients who have not experienced a subarachnoid hemorrhage or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research focuses on improving the measurement of cerebral blood flow (CBF) in patients who have experienced a subarachnoid hemorrhage (SAH). It aims to develop a novel optical monitoring technique that enhances the accuracy and specificity of CBF measurements, which are crucial for timely intervention in cases of delayed cerebral ischemia (DCI). By utilizing a new approach called interferometric diffuse optics (iDO), the research seeks to significantly increase the number of channels for detection and improve the signal quality, allowing for better monitoring of brain health. This could lead to earlier detection of complications and improved outcomes for patients.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely monitoring of cerebral blood flow, potentially reducing morbidity and mortality in patients recovering from subarachnoid hemorrhage.
How similar studies have gone: Previous research has shown promise in using optical techniques for monitoring cerebral blood flow, but this approach aims to significantly enhance the capabilities of existing methods.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Srinivasan, Vivek Jay — New York University School of Medicine
- Study coordinator: Srinivasan, Vivek Jay
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.