Measuring blood flow in the brain using advanced optical techniques

Coherence engineering of a human brain interferometer to quantitatively and specifically measure cerebral blood flow

['FUNDING_R01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11058777

This study is testing a new way to measure blood flow in the brain for patients who have had a subarachnoid hemorrhage, aiming to help doctors catch any problems earlier and improve recovery.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorNEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11058777 on ClinicalTrials.gov

What this research studies

This research focuses on improving the measurement of cerebral blood flow (CBF) in patients who have experienced a subarachnoid hemorrhage (SAH). It aims to develop a novel optical monitoring technique that enhances the accuracy and specificity of CBF measurements, which are crucial for timely intervention in cases of delayed cerebral ischemia (DCI). By utilizing a new approach called interferometric diffuse optics (iDO), the research seeks to significantly increase the number of channels for detection and improve the signal quality, allowing for better monitoring of brain health. This could lead to earlier detection of complications and improved outcomes for patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who have suffered from subarachnoid hemorrhage and are at risk for delayed cerebral ischemia.

Not a fit: Patients who have not experienced a subarachnoid hemorrhage or those with other unrelated neurological conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and timely monitoring of cerebral blood flow, potentially reducing morbidity and mortality in patients recovering from subarachnoid hemorrhage.

How similar studies have performed: Previous research has shown promise in using optical techniques for monitoring cerebral blood flow, but this approach aims to significantly enhance the capabilities of existing methods.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.