Measuring blood flow changes in the brain related to Parkinson's disease
Quantitative MR Imaging of Vascular Factors in Parkinsons Disease
This study is looking at how blood flow in the brain affects conditions like Parkinson's and Alzheimer's, using special imaging techniques to get a clearer picture of what's happening as we age, and it’s designed for people who want to understand more about the connection between blood health and symptoms like fatigue in Parkinson's.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10868582 on NIH RePORTER |
What this research studies
This research investigates how vascular health impacts neurodegenerative diseases like Parkinson's and Alzheimer's. By using advanced magnetic resonance imaging techniques, specifically Arterial Spin Labeling (ASL), the study aims to quantitatively measure blood flow and other hemodynamic changes in the aging brain without the need for contrast agents. The researchers will combine ASL with deep learning methods to enhance the accuracy and detail of these measurements, which could help in understanding the relationship between vascular changes and symptoms of Parkinson's disease, such as fatigue.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Parkinson's disease or those experiencing related symptoms.
Not a fit: Patients with other neurological conditions unrelated to vascular health may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to study vascular factors in neurodegenerative diseases, indicating a potential for success in this approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Hernandez-Garcia, Luis — University of Michigan at Ann Arbor
- Study coordinator: Hernandez-Garcia, Luis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.