Measuring biological age to understand aging and improve health.
QUANTITATIVE ASSESSMENT OF BIOLOGICAL AGE AND ITS APPLICATIONS
This study is looking to create new tools that can help measure how our bodies age at a biological level, which could give people a clearer picture of their health as they get older and help identify ways to live longer and healthier lives.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10845546 on NIH RePORTER |
What this research studies
This research focuses on developing reliable markers to quantify biological aging, which can help track the aging process in various tissues and cells. By utilizing advanced techniques like DNA methylation analysis, the study aims to create new 'DNA methylation clocks' that integrate biological and functional data. These clocks will be evaluated for their ability to respond to interventions aimed at extending lifespan and healthspan, providing insights into the fundamental biology of aging. Patients may benefit from a better understanding of their biological age and potential interventions to improve their health as they age.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults interested in understanding their biological aging process and potential interventions to improve their health.
Not a fit: Patients who are not interested in aging-related interventions or those with acute health conditions unrelated to aging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of biological age and targeted interventions that enhance health and longevity.
How similar studies have performed: Other research has shown promise in using DNA methylation as a biomarker for aging, indicating that this approach has potential for success.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Higgins-Chen, Albert Tzongyang — Yale University
- Study coordinator: Higgins-Chen, Albert Tzongyang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.