Measuring bacterial strains in the gut microbiome related to health and disease
Quantification of bacterial strain count in the human gut microbiome in health and disease
This study is looking at the different types of bacteria in the gut of people with Inflammatory Bowel Disease (IBD) to see how these bacteria might affect health and treatment outcomes, especially after procedures like fecal microbiota transplantation.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10983297 on NIH RePORTER |
What this research studies
This research investigates the diversity of bacterial strains in the gut microbiome, particularly in individuals with Inflammatory Bowel Disease (IBD). It aims to understand how the number of unique bacterial strains relates to health and disease, especially after treatments like fecal microbiota transplantation (FMT). By using advanced culturing techniques, the study will quantify the strain count in both healthy individuals and those with IBD, providing insights into the functional roles of these strains. The goal is to identify patterns that could explain why some patients respond better to treatments than others.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Inflammatory Bowel Disease (IBD) as well as healthy volunteers for comparison.
Not a fit: Patients with conditions unrelated to gut microbiome alterations or those who do not have IBD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for patients with IBD by identifying key bacterial strains that contribute to health.
How similar studies have performed: While studies have explored microbiome diversity, this research is novel in its focus on strain-level analysis and its implications for IBD treatment.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Chen-Liaw, Alice Yulan — Icahn School of Medicine at Mount Sinai
- Study coordinator: Chen-Liaw, Alice Yulan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.