Meal timing to lower health risks from night shift work

Food Timing to Mitigate Adverse Consequences of Night Work

NIH-funded research Brigham and Women's Hospital · NIH-11131254

This project will see whether eating only during your body's daytime helps night shift workers keep blood sugar and other metabolic measures healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11131254 on NIH RePORTER

What this research studies

If you work nights, researchers will ask you to follow a specific daily eating schedule timed to your biological daytime while they monitor your health. The team will use sleep and activity tracking, blood tests for glucose and other metabolic markers, and controlled feeding or meal-timing guidance over multiple days or weeks. Previous lab work showed the idea can work but used meal times that fell during sleep, so this study tests a more practical meal schedule that night workers could actually follow. The researchers aim to find a workable routine that reduces the metabolic harms linked to shift work.

Who could benefit from this research

Good fit: Ideal candidates are adults who work night shifts or have chronic circadian misalignment and are concerned about or at risk for adult-onset (type 2) diabetes.

Not a fit: People with type 1 diabetes, those unable to change when they eat, or those who cannot attend study visits are unlikely to benefit directly from joining this project.

Why it matters

Potential benefit: If successful, this approach could help night shift workers lower their risk of developing adult-onset diabetes and improve blood sugar control.

How similar studies have performed: Animal studies and tightly controlled human lab experiments suggest timing food to the biological day can help metabolism, but real-world, practical tests in night workers remain limited.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.