Matching Veterans with Chronic Pain to the Most Helpful Treatment
Optimizing Response to Chronic Pain Treatments in Veterans: Identifying Key Moderators
This project will try to match veterans with chronic pain to one of three non-drug therapies—CBT, mindfulness-based therapy, or hypnotic cognitive therapy—to see who benefits most.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11370774 on NIH RePORTER |
What this research studies
You would be randomized to one of four groups: cognitive behavioral therapy (CBT), mindfulness-based cognitive therapy (MBCT), hypnotic cognitive therapy (HYP-CT), or usual care. Before treatment, the team will collect information about your pain, mood, and other personal characteristics. Researchers will analyze which baseline features predict better responses to each therapy and build algorithms to guide future patient-treatment matching. The trial is conducted through the University of Washington and focuses on Veterans with ongoing chronic pain.
Who could benefit from this research
Good fit: Veterans with persistent chronic pain who are willing to try non-pharmacological therapies and participate in a randomized trial are the ideal candidates.
Not a fit: People who need urgent surgical or medical intervention for their pain, are not Veterans, or cannot attend or engage in therapy sessions may not benefit from joining this project.
Why it matters
Potential benefit: If successful, this work could help Veterans get the non-drug pain treatment most likely to reduce their pain and improve daily function.
How similar studies have performed: CBT, MBCT, and HYP-CT have each shown benefits for some people with chronic pain, but using pre-treatment patient factors to reliably match individuals to the best therapy is a newer approach with limited prior testing.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Jensen, Mark P — University of Washington
- Study coordinator: Jensen, Mark P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.