NIH-funded research NIH-funded research

Massachusetts Eye and Ear joins a national network to study human ear pathology

Official title: Massachusetts Eye and Ear/ Harvard Initiative for the NIDCD National Human Ear Resource Network

Funded at Massachusetts Eye and Ear Infirmary · NIH-11397011 · Data updated 2026-11-12

A national, collaborative effort will collect and study human ear tissue from autopsies to better understand deafness and balance disorders, and to share images and data with researchers.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts Eye and Ear Infirmary
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 16, 2022
Project endJuly 31, 2027
Funding year2026
Award (this year)$595,000
NIH project number5U24DC020849-05
Project IDNIH-11397011 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are individuals with a history or current condition of hearing or balance disorders, or researchers who study ear pathology and might access tissue resources.

Less likely to help

Patients whose conditions are not related to the ear or balance, or who are not researchers/clinicians in otology, may not directly benefit.

What this research studies

This project connects international experts to curate and study human temporal-bone specimens from autopsies, creating a searchable database of histology and medical history. Researchers will preserve and analyze tissue using advanced embedding and laser-based sectioning methods, then share digitized images and data for broader collaboration. The initiative also distributes unstained tissue sections to researchers for additional morphological, molecular, or genetic studies related to ear disorders. By building a larger, well-documented resource, the effort aims to accelerate discoveries about the diseases that affect hearing and balance.

Why it matters

Potential benefit: If successful, patients with hearing and balance disorders could benefit from faster scientific advances and new insights leading to better diagnostics and treatments.

How similar studies have gone: Previous efforts with large tissue collections and histopathology have enabled important discoveries in ear disease, and expanding access could amplify impact.

Where this research is happening

  • Massachusetts Eye and Ear Infirmary
    Boston, United States
    Active

Researchers

  • Principal investigator: Quesnel, Alicia M — Massachusetts Eye and Ear Infirmary
  • Study coordinator: Quesnel, Alicia M

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.