Mass General Brigham HeartShare for Heart Failure
Mass General Brigham HeartShare Clinical Center
['FUNDING_U01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11145267
This effort at Mass General Brigham aims to better understand and find new treatments for a specific type of heart failure called heart failure with preserved ejection fraction, or HFpEF.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11145267 on ClinicalTrials.gov |
What this research studies
Our team at Mass General Brigham is working to understand why treatments for heart failure with preserved ejection fraction (HFpEF) haven't been as effective as for other types of heart failure. We believe this is partly because HFpEF can look different in various people, and we don't fully know the best ways to target the condition. We bring together extensive experience in patient-focused research, using advanced tools like echocardiography and exercise testing to gather detailed information. Our goal is to identify new pathways for treatment and improve care for those living with HFpEF.
Who could benefit from this research
Good fit: Ideal candidates for related studies would include patients diagnosed with heart failure with preserved ejection fraction, as well as individuals experiencing breathlessness without this condition who could serve as comparison groups.
Not a fit: Patients with other forms of heart failure or those without symptoms of breathlessness may not directly benefit from this specific research focus.
Why it matters
Potential benefit: If successful, this work could lead to a clearer understanding of heart failure with preserved ejection fraction and help develop more effective, personalized treatments for patients.
How similar studies have performed: This initiative builds upon the team's extensive experience in human subjects research and robust clinical trials programs for heart failure with preserved ejection fraction, suggesting a foundation of prior success and knowledge.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LEWIS, GREGORY DYER — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: LEWIS, GREGORY DYER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.