Maryland PKD Clinical Research Hub
Clinical and Translational Core
This project follows adults with autosomal dominant polycystic kidney disease over time to collect health data, images, and blood samples to help improve care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11231877 on NIH RePORTER |
What this research studies
You would join a long-term observational group of adults with ADPKD in the Mid-Atlantic and have regular clinical visits plus annual phone check-ins. The team will collect your family and personal medical history, kidney and liver imaging, lab tests of organ function, patient-reported symptoms, genetic information, vascular and cognitive measures, and medication records. Participants will be asked to provide blood and other biospecimens every three years for a shared repository to support future research. A Community Advisory Board of trained patient advocates will help shape outreach, consent materials, and symptom and outcome measures to keep the study patient-centered and culturally appropriate.
Who could benefit from this research
Good fit: Adults (21 years and older) with a diagnosis of autosomal dominant polycystic kidney disease in the Mid-Atlantic region who can provide medical history, undergo imaging and testing, and participate in follow-up visits are ideal candidates.
Not a fit: People without ADPKD, children under 21, or those unwilling or unable to provide biospecimens or participate in periodic follow-up are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this effort could improve understanding of how ADPKD progresses and help tailor treatments and trial opportunities for patients.
How similar studies have performed: Longitudinal PKD registries and imaging cohorts have previously yielded valuable insights for care and trials, so this builds on successful, established approaches.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Seliger, Stephen L. — University of Maryland Baltimore
- Study coordinator: Seliger, Stephen L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.