Mapping the structure and function of the small bowel and colon
Stanford Tissue Mapping Center
['FUNDING_OTHER'] · STANFORD UNIVERSITY · NIH-10886068
This study is all about making 3D maps of the small intestine and colon to learn more about how they work and stay healthy, using tissue samples from organ donors to see how different cells interact in the gut.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10886068 on ClinicalTrials.gov |
What this research studies
This research focuses on creating detailed three-dimensional maps of the small bowel and colon to understand their structure and function better. By collecting tissue samples from deceased organ donors, researchers will analyze these tissues using advanced techniques like ATAC-seq and RNA-seq to profile chromatin and gene expression. The data will be spatially mapped to visualize how different cell types interact within the intestinal walls. This comprehensive mapping aims to enhance our understanding of intestinal health and disease.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with gastrointestinal disorders or those interested in the biological mechanisms of the small bowel and colon.
Not a fit: Patients with acute or severe gastrointestinal conditions requiring immediate clinical intervention may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of intestinal diseases.
How similar studies have performed: Other research has shown success in using similar multi-modal mapping approaches to study complex tissues, indicating a promising avenue for this investigation.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SNYDER, MICHAEL P. — STANFORD UNIVERSITY
- Study coordinator: SNYDER, MICHAEL P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.