Mapping the structure and function of brain neurons
Next-generation MORF Mice for Scalable Brainwide Morphological Mapping and Genetic Perturbation of Single Neurons
This study is looking at the different types of brain cells in mammals to understand how they work together and connect, which could help us learn more about how our brains function.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10370248 on NIH RePORTER |
What this research studies
This research aims to explore the properties of individual neurons in the mammalian brain, focusing on their molecular profiles, morphology, and connectivity. By utilizing advanced techniques, the project seeks to create a comprehensive map of neuronal structures and their functions at a large scale. This involves analyzing both genetic information and physical characteristics of neurons to better understand their roles in brain circuitry. The findings could provide insights into how different neuron types interact and contribute to brain function.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions or those interested in the genetic and structural aspects of brain function.
Not a fit: Patients with conditions unrelated to neuronal structure or function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a deeper understanding of brain function and potentially inform treatments for neurological disorders.
How similar studies have performed: Previous research in neuronal mapping and genetic profiling has shown promising results, indicating that this approach could yield valuable insights.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Yang, Xiangdong William — University of California Los Angeles
- Study coordinator: Yang, Xiangdong William
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.