Mapping the spatial organization of tumor cells in breast cancer samples
Official title: Spatial genomics analysis of tumor samples
Funded at Spatial Genomics, INC. · NIH-10918314 · Data updated 2026-11-12
This study is looking at how different cells in breast cancer tumors work together and where they are located, using special imaging tools to help improve how we diagnose and treat the disease.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Spatial Genomics, INC. NIH-funded |
| Lab location | 1 site (Pasadena, UNITED STATES) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $998,481 |
| NIH project number | 5R44CA285121-02 |
| Project ID | NIH-10918314 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with breast cancer who are undergoing biopsy procedures.
✕Less likely to help
Patients with non-breast cancer tumors or those who are not undergoing biopsy procedures may not benefit from this research.
What this research studies
This research focuses on understanding the tumor microenvironment (TME) in breast cancer by using advanced imaging techniques to visualize the spatial arrangement of various cell types within tumor samples. By identifying and profiling different cell types and their interactions in situ, the study aims to enhance cancer diagnostics and treatment options. The researchers will develop specialized reagents, instruments, and software to facilitate spatial mapping experiments on tumor tissue slices, providing insights into tumor growth and disease progression.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cancer diagnostics and personalized treatment strategies for breast cancer patients.
How similar studies have gone: Other research has shown promising results in using spatial genomics for cancer diagnostics, indicating that this approach has potential for significant advancements.
Where this research is happening
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Spatial Genomics, INC.
Pasadena, United States Active
Researchers
- Principal investigator: Frieda, Kirsten — Spatial Genomics, INC.
- Study coordinator: Frieda, Kirsten
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.