NIH-funded research R01 grant

Mapping the risk of Schistosoma mansoni for better public health control

Official title: Precision mapping of Schistosoma mansoni risk for targeted public health control and elimination

Funded at Stanford University · NIH-11106038 · Data updated 2026-11-12

This study is looking to help people with schistosomiasis by finding better ways to pinpoint areas where the disease is most common, and it will compare two quick urine tests to see which one works best for spotting the disease in those places.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startJune 5, 2024
Project endApril 30, 2029
Funding year2025
Award (this year)$629,291
NIH project number5R01AI179771-02
Project IDNIH-11106038 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in regions where schistosomiasis is endemic, particularly in low- and middle-income countries.

Less likely to help

Patients living in areas where schistosomiasis is not prevalent or those who are not infected with the parasite may not benefit from this research.

What this research studies

This research aims to improve the control and elimination of schistosomiasis, a parasitic disease affecting over 150 million people, by developing more precise mapping techniques for identifying high-risk areas. The study will compare two rapid urine antigen tests to determine their effectiveness in detecting the disease in specific geographic locations. By using a novel pooled sampling strategy, the research seeks to enhance the efficiency of targeted mass drug administration (MDA) efforts, particularly in endemic hotspots. This approach aims to provide a more cost-effective solution for public health interventions.

Why it matters

Potential benefit: If successful, this research could lead to more effective control and elimination of schistosomiasis, improving health outcomes for millions of affected individuals.

How similar studies have gone: Previous research has shown success in using targeted mapping and improved diagnostic techniques for other infectious diseases, suggesting potential for similar advancements in schistosomiasis control.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Lo, Nathan — Stanford University
  • Study coordinator: Lo, Nathan

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.