Mapping the proteins that support our cells and tissues
Thinking outside the cell: Leveraging HuBMAP data to build the human ECM atlas
This study is looking at a special network of proteins that support our cells and help them work properly, to better understand how changes in this network might affect health and diseases like Alport syndrome.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-11090355 on NIH RePORTER |
What this research studies
This research investigates the extracellular matrix (ECM), a vital network of proteins that not only provides structural support to cells but also plays a crucial role in regulating cellular functions. By analyzing the composition and changes of the ECM in various tissues and diseases, the project aims to uncover how these proteins influence health and disease processes. The research employs advanced techniques to study ECM proteins at a detailed level, which could lead to a better understanding of conditions like Alport syndrome and other related diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions related to ECM abnormalities, such as Alport syndrome or other connective tissue disorders.
Not a fit: Patients with conditions unrelated to ECM dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for diseases linked to ECM dysfunction, improving patient outcomes.
How similar studies have performed: Other research has shown promising results in understanding the ECM's role in various diseases, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Naba, Alexandra — University of Illinois at Chicago
- Study coordinator: Naba, Alexandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.