Mapping the molecular differences in atopic dermatitis based on ethnicity and severity.
Developing a Molecular Map of Atopic Dermatitis Across Ethnicity and Severity Subtypes.
This study is looking at how atopic dermatitis (AD) shows up differently in people from various backgrounds and with different levels of severity, so we can find better ways to treat it for everyone, no matter where they live.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11052650 on NIH RePORTER |
What this research studies
This research investigates how atopic dermatitis (AD) varies among different ethnic groups and levels of disease severity. By analyzing skin and blood samples from patients in Africa, Asia, and the United States, the study aims to identify distinct molecular phenotypes that could inform tailored treatment strategies. The researchers hypothesize that severe AD may involve systemic inflammation, requiring different therapeutic approaches compared to mild cases. This work seeks to enhance understanding of AD and improve treatment outcomes for diverse patient populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with moderate-to-severe atopic dermatitis from diverse ethnic backgrounds, particularly those from Africa and Asia.
Not a fit: Patients with mild atopic dermatitis or those not belonging to the studied ethnic groups may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatments for patients with atopic dermatitis based on their specific ethnic background and disease severity.
How similar studies have performed: Other research has shown promising results in understanding ethnic differences in skin conditions, suggesting that this approach could yield valuable insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Guttman, Emma — Icahn School of Medicine at Mount Sinai
- Study coordinator: Guttman, Emma
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.