Mapping the metabolic profiles of cancer tumors
Official title: Creation of the Human Cancer Metabolome Atlas
Funded at Univ of North Carolina Chapel Hill · NIH-10882695 · Data updated 2026-11-12
This study is building a helpful resource that gathers and analyzes metabolic information from over 2000 tumors to better understand how different types and stages of cancer affect metabolism, which will support doctors and researchers in creating more effective treatments for cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $661,831 |
| NIH project number | 1R01CA282657-01A1 |
| Project ID | NIH-10882695 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with various types of cancer who are undergoing treatment and have tumor samples available for analysis.
✕Less likely to help
Patients with non-cancerous conditions or those whose tumors cannot be analyzed through the proposed methodologies may not benefit from this research.
What this research studies
This research aims to create a comprehensive database called the Human Cancer Metabolome Atlas, which will collect and analyze metabolic data from over 2000 patient-derived tumors. By utilizing advanced mass spectrometry-based metabolomics, the project seeks to understand how different tumor types and stages influence their metabolic characteristics. This information will be made publicly available to aid researchers and clinicians in developing targeted cancer therapies based on tumor metabolism. The goal is to fill a critical gap in cancer research by providing insights into the metabolic reprogramming that occurs in tumors.
Why it matters
Potential benefit: If successful, this research could lead to more effective, metabolism-targeted cancer treatments that improve patient outcomes.
How similar studies have gone: Previous research has successfully utilized similar approaches in genomics and proteomics, indicating a strong potential for success in metabolomics as well.
Where this research is happening
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Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Rushing, Blake Richey — Univ of North Carolina Chapel Hill
- Study coordinator: Rushing, Blake Richey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.