Mapping the human kidney in 3D using advanced imaging techniques
Vanderbilt University Biomolecular Multimodal Imaging Center for 3-Dimensional Mapping of the Human Kidney
This study is working to create a detailed 3D map of the human kidney to better understand how different types of kidney cells work together, which could help improve our knowledge of kidney health and diseases for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University NIH-funded |
| Lab location | 1 site (Nashville, UNITED STATES) |
| Project ID | NIH-10884880 on NIH RePORTER |
What this research studies
This research aims to create a detailed 3D molecular atlas of the human kidney by using various advanced imaging techniques. It will integrate methods such as imaging mass spectrometry and single-cell RNA sequencing to explore how different cell types within the kidney interact and function together. By collecting and analyzing kidney tissue samples, the project seeks to enhance our understanding of kidney anatomy and cellular organization, which could lead to better insights into kidney health and disease.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with healthy kidneys or those with kidney diseases who are willing to provide tissue samples for analysis.
Not a fit: Patients who have undergone kidney transplants or those with acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve our understanding of kidney function and disease, potentially leading to better diagnostic and therapeutic strategies for kidney-related conditions.
How similar studies have performed: Other research has successfully utilized multimodal imaging approaches to map complex organ structures, indicating that this method has the potential for significant breakthroughs in understanding kidney biology.
Where this research is happening
Nashville, UNITED STATES
- Vanderbilt University — Nashville, United States (Active)
Researchers
- Principal investigator: Spraggins, Jeffrey M — Vanderbilt University
- Study coordinator: Spraggins, Jeffrey M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.