Mapping the Human Heart in Detail
Center for multidimensional atlas of the human heart
This project is creating a detailed map of the human heart to better understand how it works and changes throughout life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11087697 on NIH RePORTER |
What this research studies
Our hearts are incredibly complex, with many different types of cells and structures that perform vital functions. We don't fully understand how these cells' unique molecular features, locations, and interactions contribute to heart health and disease. This project aims to create a comprehensive map of the heart, looking at molecular and cellular changes across a person's lifetime using advanced single-cell and imaging technologies. The goal is to build a publicly available, searchable database that combines detailed heart data with clinical information.
Who could benefit from this research
Good fit: This foundational research focuses on understanding the human heart at a cellular and molecular level, potentially benefiting anyone with heart conditions in the future.
Not a fit: Patients seeking immediate treatment or direct clinical intervention would not receive benefit from this foundational mapping project.
Why it matters
Potential benefit: If successful, this work could provide a foundational understanding of the heart, leading to new ways to research and treat heart diseases.
How similar studies have performed: While comprehensive human organ atlases are a relatively new and ambitious endeavor, similar efforts in other organs are showing promise in advancing biological understanding.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Tan, Kai — Children's Hosp of Philadelphia
- Study coordinator: Tan, Kai
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.