Mapping the genetic factors that influence ovarian cancer
High-throughput Epigenomic Mapping of Regulatory Elements in Ovarian Cancer at Basepair Resolution
This study is looking at how certain factors in ovarian cancer, especially the clear cell and endometrioid types, influence the disease beyond just genetics, with the goal of creating better ways to diagnose and treat patients based on their specific cancer type.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Van Andel Research Institute NIH-funded |
| Lab location | 1 site (Grand Rapids, United States) |
| Project ID | NIH-10892029 on NIH RePORTER |
What this research studies
This research investigates the epigenomic landscape of ovarian cancer, focusing on how regulatory elements affect the disease at a basepair resolution. By analyzing different histotypes of ovarian cancer, particularly clear cell and endometrioid types, the study aims to uncover the non-genetic mechanisms that contribute to their distinct clinical behaviors. Patients may benefit from the development of novel bioinformatics tools and technologies that could lead to improved diagnostic and therapeutic strategies tailored to their specific cancer type.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with clear cell or endometrioid ovarian cancer.
Not a fit: Patients with other types of ovarian cancer or those without a diagnosis of ovarian cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and personalized care for ovarian cancer patients.
How similar studies have performed: Other research has shown success in utilizing epigenomic mapping to understand cancer biology, indicating that this approach has potential for impactful findings.
Where this research is happening
Grand Rapids, United States
- Van Andel Research Institute — Grand Rapids, United States (Active)
Researchers
- Principal investigator: Shen, Hui — Van Andel Research Institute
- Study coordinator: Shen, Hui
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.