Mapping the Genes of Bacteria in Your Mouth
Official title: Metapangenomics of the Oral Microbiome
Funded at Ada Forsyth Institute, INC. · NIH-11125752 · Data updated 2026-11-12
This project helps us understand the genes within the bacteria in your mouth to learn how they affect your health and well-being.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ada Forsyth Institute, INC. NIH-funded |
| Lab location | 1 site (Somerville, UNITED STATES) |
| Project start | July 1, 2021 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $596,768 |
| NIH project number | 5R01DE030136-05 |
| Project ID | NIH-11125752 on NIH RePORTER |
Who could benefit from this research
✓Could help
This foundational bioinformatics project does not directly involve patient participation at this time.
✕Less likely to help
Patients looking for immediate treatment options or direct clinical interventions will not receive benefit from this foundational research.
What this research studies
Our mouths are home to many different types of bacteria, forming a complex community called the oral microbiome. This project aims to understand the genes within these bacteria to see how they interact with each other and with our bodies. By analyzing existing genetic information from large databases, we hope to discover how specific genes influence the bacteria's roles in oral health and disease. This deeper understanding is key to developing new ways to keep our mouths healthy and prevent problems.
Why it matters
Potential benefit: If successful, this work could lead to new strategies for preventing and treating oral diseases by better understanding the bacteria in our mouths.
How similar studies have gone: While pangenomic and metagenomic analyses are established, this project applies a novel 'metapangenomics' approach to existing oral microbiome data.
Where this research is happening
-
Ada Forsyth Institute, INC.
Somerville, United States Active
Researchers
- Principal investigator: Borisy, Gary G — Ada Forsyth Institute, INC.
- Study coordinator: Borisy, Gary G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.