Mapping the different diseases of the human lung
Official title: Cross-Disease Multi-Modality Mapping of the Human Lung
Funded at University of California, San Diego · NIH-10975746 · Data updated 2026-11-12
This study is looking at how different lung diseases work by examining lung cells closely, using cutting-edge technology to find out what makes each disease unique, which could help us create better treatments for both kids and adults with lung issues.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $747,861 |
| NIH project number | 1U01HL175452-01 |
| Project ID | NIH-10975746 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with various lung diseases, particularly those aged 21 and older.
✕Less likely to help
Patients with non-lung-related conditions or those under 21 years old may not receive benefit from this research.
What this research studies
This research investigates the diverse mechanisms behind various lung diseases by analyzing high-resolution datasets of lung cells. It utilizes advanced technologies like single nucleus RNA sequencing and ATAC sequencing to compare the cellular and molecular profiles of different lung conditions. The goal is to identify unique signatures that differentiate these diseases, which could lead to more effective treatments. By focusing on both pediatric and adult lung diseases, the research aims to enhance our understanding of lung biology and disease progression.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for a range of lung diseases.
How similar studies have gone: Previous research has shown success in using similar multi-modal approaches to understand complex diseases, indicating a promising avenue for this investigation.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Sun, Xin — University of California, San Diego
- Study coordinator: Sun, Xin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.