Mapping the connections in the mouse brain using advanced imaging techniques
BRAIN CONNECTS: Center for a pipeline of high throughput integrated volumetric electron microscopy for whole mouse brain connectomics
['FUNDING_OTHER'] · ALLEN INSTITUTE · NIH-10917205
This study is all about making a detailed map of how different cells in the mouse brain connect with each other, which could help us understand brain disorders better and find new treatments for them.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ALLEN INSTITUTE (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10917205 on ClinicalTrials.gov |
What this research studies
This research focuses on creating a detailed map of the connections between different cell types in the mouse brain using high-throughput integrated volumetric electron microscopy. By improving imaging techniques and data processing methods, the project aims to systematically uncover the wiring diagram of the brain, which is crucial for understanding how brain functions are organized. The research builds on previous successes in mapping simpler organisms and seeks to apply those insights to the more complex mouse brain. Patients can benefit from this research as it may lead to new insights into brain disorders and potential treatments.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with neurological conditions or those interested in brain health and function.
Not a fit: Patients with conditions unrelated to brain function or those not residing in the geographic area of the research may not receive direct benefits.
Why it matters
Potential benefit: If successful, this research could provide critical insights into brain connectivity that may lead to improved understanding and treatment of neurological disorders.
How similar studies have performed: Previous research in simpler organisms like C. elegans and Drosophila has shown success in mapping brain connections, suggesting that this approach could be effective in mice as well.
Where this research is happening
SEATTLE, UNITED STATES
- ALLEN INSTITUTE — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MACARICO DA COSTA, NUNO — ALLEN INSTITUTE
- Study coordinator: MACARICO DA COSTA, NUNO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.