Mapping the cellular networks involved in pulmonary fibrosis
Official title: Spatiotemporal Atlas of Cellular Networks and Ultrastructural States Mediating the Progression and Resolution of Pulmonary Fibrosis
Funded at Stanford University · NIH-10904633 · Data updated 2026-11-12
This study is exploring how pulmonary fibrosis affects the lungs over time, aiming to understand the different cells involved in the disease, which could help develop better ways to diagnose and treat people with this condition.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | July 18, 2023 |
| Project end | July 17, 2026 |
| Funding year | 2024 |
| Award (this year) | $76,756 |
| NIH project number | 5F32HL167318-02 |
| Project ID | NIH-10904633 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with pulmonary fibrosis, particularly those with idiopathic forms or those affected by chronic conditions or respiratory infections.
✕Less likely to help
Patients with pulmonary fibrosis caused by known factors, such as specific genetic mutations or environmental exposures, may not benefit directly from this research.
What this research studies
This research investigates the complex biological mechanisms behind pulmonary fibrosis (PF), a serious lung condition affecting millions. By creating a detailed atlas that captures the spatial and temporal changes in lung tissue during PF progression and resolution, the study aims to identify key cellular interactions and pathways involved in the disease. The approach combines advanced techniques in multi-omics and cellular characterization to better understand how different cell types contribute to fibrosis and its resolution. This knowledge could lead to improved diagnostic and therapeutic strategies for patients suffering from PF.
Why it matters
Potential benefit: If successful, this research could lead to new treatments and better management strategies for patients with pulmonary fibrosis.
How similar studies have gone: Previous research has shown promise in understanding the cellular mechanisms of fibrosis, but this specific approach of creating a spatiotemporal atlas is novel and untested.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Guo, Jason Liwei — Stanford University
- Study coordinator: Guo, Jason Liwei
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.