Mapping the cells in knee cartilage to understand joint health
High resolution 3D mapping of cellular heterogeneity within multiple types of mineralized tissues
['FUNDING_OTHER'] · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · NIH-10816791
This study is all about making detailed maps of the cells in your knee cartilage to better understand how they work and what happens when they start to break down, especially in conditions like osteoarthritis.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CONNECTICUT SCH OF MED/DNT (nih funded) |
| Locations | 1 site (FARMINGTON, UNITED STATES) |
| Trial ID | NIH-10816791 on ClinicalTrials.gov |
What this research studies
This research focuses on creating detailed maps of the cells that make up the cartilage in the knee joint. By using advanced imaging techniques, researchers will identify and locate different types of cells within the cartilage, which is crucial for maintaining joint health. The study combines molecular expression analysis with antibody detection methods to provide a comprehensive view of how these cells function and interact. This information could help in understanding how cartilage degeneration occurs, particularly in conditions like osteoarthritis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing knee joint issues, particularly those at risk for or diagnosed with osteoarthritis.
Not a fit: Patients with knee joint problems unrelated to cartilage degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for knee joint diseases, particularly osteoarthritis.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques to study cellular structures in various tissues, indicating that this approach could yield valuable insights.
Where this research is happening
FARMINGTON, UNITED STATES
- UNIVERSITY OF CONNECTICUT SCH OF MED/DNT — FARMINGTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROWE, DAVID W. — UNIVERSITY OF CONNECTICUT SCH OF MED/DNT
- Study coordinator: ROWE, DAVID W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.