Mapping the cell types and structures of developing human brains
Spatiotemporal epigenomic and chromosomal architectural cell atlas of developing human brains
This study is looking at how different types of brain cells grow and change over time, which could help us understand more about brain development and how it relates to conditions like autism, so that patients can benefit from new insights into their health.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-10884304 on NIH RePORTER |
What this research studies
This research investigates the various cell types and their developmental processes in the human brain, particularly focusing on how these cells change over time. By utilizing advanced techniques like single-cell DNA profiling and three-dimensional chromosomal mapping, the study aims to identify the unique characteristics of brain cells during development. This information could help in understanding how certain genetic factors contribute to neuropsychiatric disorders. Patients may benefit from insights gained about brain development and its implications for conditions like autism.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include children and young adults, particularly those with neurodevelopmental disorders such as autism.
Not a fit: Patients with fully developed brains or those outside the age range of 0-21 years may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for neuropsychiatric disorders in children and young adults.
How similar studies have performed: Previous research has shown success in using similar epigenomic and transcriptomic approaches to understand brain development and associated disorders.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Luo, Chongyuan — University of California Los Angeles
- Study coordinator: Luo, Chongyuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.