Mapping the brain's serotonin system

Building a Granular Brain-Wide Map of the Serotonin System

['FUNDING_R01'] · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · NIH-11092910

This study is looking at how a brain chemical called serotonin affects our thoughts and feelings, with the goal of finding better treatments for mental health issues by understanding how serotonin works in the brain.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorNEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11092910 on ClinicalTrials.gov

What this research studies

This research investigates how serotonin, a key brain chemical, influences various cognitive and emotional functions. By creating a detailed map of serotonin pathways in the brain, the project aims to understand how these pathways affect behaviors such as stress response, social interactions, and aggression. Using advanced techniques, researchers will analyze the connections and functions of serotonin-producing neurons, which could lead to more targeted treatments for neuropsychiatric conditions. This work is crucial for developing therapies that address the specific needs of patients rather than using broad-spectrum medications.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 who are experiencing neuropsychiatric conditions related to serotonin dysfunction.

Not a fit: Patients under 21 or those with conditions unrelated to serotonin may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatments for mental health conditions by targeting specific serotonin pathways.

How similar studies have performed: Previous research has shown promise in mapping brain systems and targeting neurotransmitter pathways, indicating potential for success in this novel approach.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.