Mapping the brain's molecular changes in Alzheimer's disease
Creating a region- specific biomolecular atlas of the brain of Alzheimer’s disease
This study is looking at how Alzheimer's disease changes the brain at a molecular level, using advanced imaging to create a detailed map of these changes, which could help develop better treatments for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10889101 on NIH RePORTER |
What this research studies
This research investigates the specific molecular changes in different regions of the brain affected by Alzheimer's disease. By using advanced imaging technology, the study aims to create a detailed map of how various molecular classes, such as proteins and lipids, are altered in Alzheimer's. This approach allows for a better understanding of the disease's progression and its impact on brain function. Patients may benefit from insights that could lead to more targeted therapies and interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or related dementias.
Not a fit: Patients with early-stage cognitive decline not yet diagnosed with Alzheimer's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for Alzheimer's disease.
How similar studies have performed: Previous research has shown success in using similar imaging techniques to study brain diseases, indicating a promising approach.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Li, Lingjun — University of Wisconsin-Madison
- Study coordinator: Li, Lingjun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.