Mapping the 3D structure of ovarian cancer to understand treatment resistance
Official title: 3D Spatial Multi-Omics Profiling of Ovarian Cancer
Funded at University of Tx Md Anderson Can Ctr · NIH-10994265 · Data updated 2026-11-12
This study is looking at high-grade serous ovarian cancer to create a detailed map of how it spreads and why some people don’t respond well to chemotherapy, with the hope of finding better treatments for patients like you.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,004,570 |
| NIH project number | 1U01CA294459-01 |
| Project ID | NIH-10994265 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with advanced high-grade serous ovarian cancer.
✕Less likely to help
Patients with early-stage ovarian cancer or other types of ovarian cancer may not benefit from this research.
What this research studies
This research investigates high-grade serous ovarian cancer (HGSOC), the most common type of ovarian cancer, by creating a detailed three-dimensional atlas of the disease. The project aims to understand how HGSOC spreads and why some patients do not respond to chemotherapy. By utilizing advanced molecular and cellular profiling techniques, the research team will analyze samples from a diverse group of patients diagnosed with advanced HGSOC. The findings could lead to improved treatment strategies and better patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for ovarian cancer, potentially increasing survival rates.
How similar studies have gone: Previous research has shown promise in using multi-omics approaches to understand cancer biology, suggesting that this method could yield valuable insights.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Mok, Samuel C — University of Tx Md Anderson Can Ctr
- Study coordinator: Mok, Samuel C
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.