Mapping the 3D structure and function of the bowel
Organ Specific Project
This study is working on making a detailed 3D map of the small intestine and colon to better understand how they work and how diseases can affect them, using samples from different people to get a complete picture.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10886070 on NIH RePORTER |
What this research studies
This research aims to create a detailed 3D map of the gastrointestinal tract, focusing on the small bowel and colon. By using advanced techniques like single-nuclei RNA sequencing and multiplex immunoassays, the project will analyze the gene expression and spatial relationships of various cell types within the bowel. This comprehensive mapping will help researchers understand how the bowel functions normally and how it can be affected by diseases. The study will involve tissues from diverse individuals to ensure a broad understanding of bowel physiology.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with gastrointestinal conditions or those interested in understanding bowel health.
Not a fit: Patients with no gastrointestinal issues or those outside the demographic diversity targeted by the study may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of gastrointestinal diseases and their impact on overall health.
How similar studies have performed: Other research has shown success in mapping organ systems using similar high-resolution techniques, indicating a promising approach.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Snyder, Michael P. — Stanford University
- Study coordinator: Snyder, Michael P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.