Mapping Signals from Fat Cells to Understand Diabetes
An Encyclopedia of the Adipose Tissue Secretome to Identify Mediators of Health and Disease
This project aims to discover the many signals released by fat cells to understand how they influence conditions like type 2 diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11140511 on NIH RePORTER |
What this research studies
Fat cells do more than store energy; they also send out signals that affect our body's health. When these signals go wrong, it can lead to problems like insulin resistance and type 2 diabetes. This project is creating a complete map of all the different signals that fat cells release, both in healthy states and in conditions like diabetes. By understanding these signals, we hope to find new ways to keep our bodies healthy and address metabolic disorders. This work involves looking at these signals in both laboratory models and in people.
Who could benefit from this research
Good fit: Individuals with or at risk for type 2 diabetes may be considered for future observational components or sample donations.
Not a fit: Patients whose conditions are unrelated to fat cell signaling or metabolic disorders would likely not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to prevent or treat type 2 diabetes and other metabolic disorders by targeting specific signals from fat cells.
How similar studies have performed: While the concept of fat cell signaling is known, this project aims to create the first comprehensive "encyclopedia" of these signals, making it a novel and foundational effort.
Where this research is happening
New York, United States
- Rockefeller University — New York, United States (Active)
Researchers
- Principal investigator: Cohen, Paul — Rockefeller University
- Study coordinator: Cohen, Paul
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.